Principles and Features of Chromatography 9 Analysis and Description of Chromatograms 13 Voidage and Porosity 13 Retention Times and Capacity Factors 16 Efficiency of Chromatographic Separations 17 Resolution 20 Pressure Drop 23 Mass Transfer and Fluid Dynamics 25 Principles of Mass Transfer 25 Fluid Distribution in the Column 27 Packing Nonidealities 28 Extra-Column Effects 29 Equilibrium Thermodynamics 29 Definition of Isotherms 29 Models of Isotherms 31 Single-Component Isotherms 31 Multicomponent Isotherms Based on the Langmuir Model 33 Competitive Isotherms Based on the Ideal Adsorbed Solution Theory 34 Steric Mass Action Isotherms 37
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Introduction 1 Henner Schmidt-Traub and Reinhard DitzĬhromatography, Development, and Future Trends 1 Focus of the Book 4 Suggestions on How to Read this Book 4 References 6įundamentals and General Terminology 9 Andreas Seidel-MorgensternĢ.1 2.2 2.2.1 2.2.2 2.2.3 2.2.4 2.2.5 2.3 2.3.1 2.3.2 2.3.3 2.3.4 2.4 2.4.1 2.4.2 2.4.2.1 2.4.2.2 2.4.2.3 Printed on acid-free paper 10 9 8 7 6 5 4 3 2 1Ĭontents Preface xv About the Editors xvii List of Abbreviations xix Notation xxiii 1 Germany Typesetting SPi Global, Chennai, India Printing and Binding Print ISBN: 978-6-4 ePDF ISBN: 978-1-6 ePub ISBN: 978-3-0 oBook ISBN: 978-4-7 Cover Design Formgeber, Mannheim, used in this book, even when not specifically marked as such, are not to be considered unprotected by law. No part of this book may be reproduced in any form – by photoprinting, microfilm, or any other means – nor transmitted or translated into a machine language without written permission from the publishers. 12, 69469 Weinheim, Germany All rights reserved (including those of translation into other languages). The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie detailed bibliographic data are available on the Internet at. Bibliographic information published by the Deutsche Nationalbibliothek The cover image of a column head is reproduced by courtesy of Merck, Germany.Īpplied for British Library Cataloguing-in-Publication DataĪ catalogue record for this book is available from the British Library. The cover image of a multicolumn continuous plant is reproduced by courtesy of Novasep, France. Otto-von-Guericke-Universität Institut für Verfahrenstechnik Lehrstuhl für Chemische Verfahrenstechnik and Max-Planck-Institut für Dynamik komplexer technischer SystemeSandtorstraße 1 Universitätsplatz 239106 Magdeburg Germany Cover
Merck KGaA Life Science - Bioprocessing Purification R&D Frankfurter Str. Readers are advised to keep in mind that statements, data, illustrations, procedural details or other items may inadvertently be inaccurate.
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Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. 70 44227 Dortmund GermanyĪll books published by Wiley-VCH are carefully produced. TU Dortmund Fakultüt für Bio- und Chemieingenieurwesen Lehrstuhl für Anlagen- und Prozesstechnik Emil-Figge-Str. Preparative Chromatography Edited by Henner Schmidt-Traub Michael Schulte Andreas Seidel-MorgensternĮditors Prof.
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